University of Wisconsin-Madison

Fluorescence image of “UW” written with rhodamine-labeled modular bone morphogenetic peptide (mBMP) solution on cortical bone, March, 2013. For more information, click here. Image provided by Jae Sung Lee.

Bone-like mineral coating created on poly(lactide-co-glycolide) substrate by incubating in modified simulated body fluid m(SBF). Image provided by Jae Sung Lee.

Endothelial progenitor cells (EPCs, green) in an endothelial cell (EC, red) tubulogenesis assay. EPCs secrete a variety of pro-angiogenic soluble factors that induce tubule formation of ECs. Image provided by Matt Parlato.

Computed tomography (CT) scan of the mouse hindlimb digits. The P3 bones (distal bones) are the bones of interest, capable of regenerating. Image provided by Connie S. Chamberlain.

Murphy Group Bioinspired Materials Laboratory (BML): creating new biomaterials that accelerate scientific discovery and improve medical treatment.

Welcome to the Murphy Group Bioinspired Materials Lab (BML) at the University of Wisconsin-Madison.

We are building innovative biomaterials to address significant challenges in biology and medicine. We bring together chemists, biologists, materials scientists, and engineers to create new materials we refer to as “bioinspired materials”. Our materials are “bioinspired” because they mimic some of the fascinating ways that nature builds materials – from sea shells to human organs. We work closely with biologists to make fundamental scientific discoveries. We also partner with clinicians to create medical devices that can regenerate diseased or damaged tissues. We are driven to achieve high impact by pursuing groundbreaking discoveries, translating discoveries into new medical treatments, and training the next generation of leaders in regenerative medicine.