Hannah Martin

Position title: Graduate Student, Comparative Biomedical Sciences, DVM/PhD Program

Education Background: B.E. Biomedical Engineering, Vanderbilt University

Research Description: Sustained, localized cytokine delivery for cancer immunotherapy.

Publications:

1. Fontana G, Martin H, Lee JS, Schill K, Hematti P, Murphy W. Mineral-coated microparticles enhance mRNA-based transfection of human bone marrow cells. Molecular Therapy: Nucleic Acids, 2019. 18:455-464.

2. Kerzner B, Martin H, Weiser M, Fontana G, Russell N, Murphy W, Lund E, Doro C. A reliable and reproducible critical-sized segmental femoral defect model in rats stabilized with a custom external fixator. Journal of Visualized Experiments, 2019. (145):e59206.

3. Zhu C, Li M, Vincent T, Martin H, Crouch B, Martinez A, Madonna M, Palmer G, Dewhirst M, Ramanujam N. Simultaneous optical quantification of key metabolic and vascular endpoints reveals tumor metabolic diversity in murine breast tumor models. Journal of Biophotonics, 2018. 12(4):e201800372.

4. Zhu C, Martin H, Crouch B, Martinez A, Li M, Palmer G, Dewhirst M, Ramanujam N. Near-simultaneous quantification of glucose uptake, mitochondrial membrane potential, and vascular parameters in murine flank tumors using quantitative diffuse reflectance and fluorescence spectroscopy. Biomedical Optics Express, 2018. 9(7):3399-3412.

5. Martinez A, McCachren III S, Lee M, Murphy H, Zhu C, Martin H, Erkanli A, Rajaram N, Ashcraft K, Fontanella A, Dewhirst M, Ramanujam N. Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging. Scientific Reports, 2018. 8(1):4171.

6. Zhu C*, Martinez A*, Martin H, Li M, Crouch B, Carlson D, Haystead TAJ, Ramanujam N. Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer. Scientific Reports, 2017. 7(1):13772. *Authors contributed equally.

7. Hu F, Martin H, Martinez A, Everitt J, Erklani A, Lee W, Dewhirst M, Ramanujam N. Distinct angiogenic changes during carcinogenesis defined by novel label-free dark-field imaging in a hamster cheek pouch model. Cancer Research, 2017. 77(24):7109-7119.

Awards:

Boehringer Ingelheim Veterinary Summer Scholar

National Merit Scholarship