“The Forward BIO Initiative will have everything it takes to amplify the impact of Wisconsin’s innovations in biomanufacturing,” said William Murphy, a professor of biomedical engineering and orthopedics at the University of Wisconsin-Madison and a …
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Big Idea: Using plant leaves as scaffolding to grow human cells
Murphy’s team found that leaf structures not only have an “incredible ability” for mass transport, moving and expelling fluids rapidly and efficiently from one end to the other, but that human cells pattern themselves in …
Advance furthers stem cells for use in drug discovery, cell therapy
This week, a UW–Madison team reports in Nature Biomedical Engineering that they have jumped a major hurdle on the path toward wider use of stem cells. Using an automated screening test that they devised, William …
UW-Madison scientists, inspired by old bones, find new strategy for drug delivery
UW-Madison scientists, inspired by proteins found intact in centuries-old human bones, created a mineral coating that mimics bone and appears to keep proteins stable. “What’s needed is a delivery system that remains localized, releases the …
Synthetic alternatives to Matrigel for toxicity screening and stem cell expansion
Arrays of synthetic hydrogels outperforms Matrigel in the screening for vascular-disrupting compounds and in supporting the expansion of human embryonic stem cells. The paper is published in nature biomedical Engineering.
UW-Madison scientists grow functional artery cells from stem cells, truly functional arterial cells reportedly created for the first time
In a step toward one of stem cell science’s chief goals, UW-Madison researchers have grown functional human artery cells that helped lab mice survive heart attacks. “This work provides valuable proof that we can eventually …
UW-Madison research team at McPherson Eye Research Institute awarded NIH Grant to Reverse Blindness
Gamm’s team (includes scientist Joe Phillips; neuroscience professors Tim Gomez and Xinyu Zhao, and bioengineers Justin Williams and William Murphy) awarded NIH Grant to Reverse Blindness. Madison, Wisconsin – A UW-Madison research team has been …
Steering Organoids Toward Discovery
SELF-DRIVING STEM CELLS ARE OPENING A WORLD OF POSSIBILITIES, INCLUDING DRUG TESTING AND TISSUE SOURCING. Since the 1980s, stem cells’ shape-shifting abilities have wowed scientists. With proper handling, a few growth factors, and some time, …
Stratatech will establish skin tissue inventory in case of natural or man-made emergency
Stratatech receives $247 million contract to develop skin product. Stratatech will use the contract money to fund a final phase clinical trial for its flagship StrataGraft product, which is delivered to users frozen, giving it …
3D brain-on-a-chip helps predict drug neurotoxicity
NIH-funded engineered brain tissue identifies toxins correctly 9 out of 10 times To help test the toxicity of new drugs, NIBIB researchers have engineered a 3D brain organoid—a miniature organ structure that attempts to mimic the …