UW-Madison scientists, inspired by proteins found intact in centuries-old human bones, created a mineral coating that mimics bone and appears to keep proteins stable. “What’s needed is a delivery system that remains localized, releases the …
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Synthetic alternatives to Matrigel for toxicity screening and stem cell expansion
Arrays of synthetic hydrogels outperforms Matrigel in the screening for vascular-disrupting compounds and in supporting the expansion of human embryonic stem cells. The paper is published in nature biomedical Engineering.
UW-Madison scientists grow functional artery cells from stem cells, truly functional arterial cells reportedly created for the first time
In a step toward one of stem cell science’s chief goals, UW-Madison researchers have grown functional human artery cells that helped lab mice survive heart attacks. “This work provides valuable proof that we can eventually …
UW-Madison research team at McPherson Eye Research Institute awarded NIH Grant to Reverse Blindness
Gamm’s team (includes scientist Joe Phillips; neuroscience professors Tim Gomez and Xinyu Zhao, and bioengineers Justin Williams and William Murphy) awarded NIH Grant to Reverse Blindness. Madison, Wisconsin – A UW-Madison research team has been …
Steering Organoids Toward Discovery
SELF-DRIVING STEM CELLS ARE OPENING A WORLD OF POSSIBILITIES, INCLUDING DRUG TESTING AND TISSUE SOURCING. Since the 1980s, stem cells’ shape-shifting abilities have wowed scientists. With proper handling, a few growth factors, and some time, …
Stratatech will establish skin tissue inventory in case of natural or man-made emergency
Stratatech receives $247 million contract to develop skin product. Stratatech will use the contract money to fund a final phase clinical trial for its flagship StrataGraft product, which is delivered to users frozen, giving it …
3D brain-on-a-chip helps predict drug neurotoxicity
NIH-funded engineered brain tissue identifies toxins correctly 9 out of 10 times To help test the toxicity of new drugs, NIBIB researchers have engineered a 3D brain organoid—a miniature organ structure that attempts to mimic the …
U.S. Senator Baldwin Pushes For New Standards In Regenerative Medicine Industry
U.S. Sen. Tammy Baldwin has introduced new legislation to create industry standards for regenerative medicine. The bill would create a public-private board to set guidelines for regenerative medical products, including those developed from stem cells. Dr. …
New way of developing tissue mimics brain function, has potential to eventually replace animal testing
UW scientists develop brain-like structure to improve drug safety testing. University of Wisconsin scientists have created a structure that mimics brain function and may be used to determine the safety of pharmaceutical drugs and industrial …
“Brain in a Dish” could replace toxic animal test
Scientific American and Francis Collins, NIH director, discuss the potential potential impacts of Michael Schwartz’s human brain models on hydrogels. These “Brain in a Dish” models may provide a fast, low cost way to screen …